# Combination Chemotherapy, Radiation Therapy, and an Autologous Peripheral Blood Stem Cell Transplant in Treating Young Patients With Atypical Teratoid/Rhabdoid Tumor of the Central Nervous System

> **NCT00653068** · PHASE3 · COMPLETED · sponsor: **Children's Oncology Group** · enrollment: 70 (actual)

## Conditions studied

- Childhood Atypical Teratoid/Rhabdoid Tumor

## Interventions

- **RADIATION:** 3-Dimensional Conformal Radiation Therapy
- **PROCEDURE:** Autologous Hematopoietic Stem Cell Transplantation
- **DRUG:** Carboplatin
- **DRUG:** Cisplatin
- **DRUG:** Cyclophosphamide
- **DRUG:** Etoposide
- **BIOLOGICAL:** Filgrastim
- **OTHER:** Laboratory Biomarker Analysis
- **DRUG:** Leucovorin Calcium
- **DRUG:** Methotrexate
- **DRUG:** Thiotepa
- **DRUG:** Vincristine Sulfate

## Key facts

- **NCT ID:** NCT00653068
- **Lead sponsor:** Children's Oncology Group
- **Sponsor class:** NETWORK
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2009-02-10
- **Primary completion:** 2016-09-27
- **Final completion:** 2024-03-31
- **Target enrollment:** 70 (ACTUAL)
- **Last updated:** 2024-04-23

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00653068

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00653068, "Combination Chemotherapy, Radiation Therapy, and an Autologous Peripheral Blood Stem Cell Transplant in Treating Young Patients With Atypical Teratoid/Rhabdoid Tumor of the Central Nervous System". Retrieved via AI Analytics 2026-06-12 from https://api.ai-analytics.org/clinical/NCT00653068. Licensed CC0.

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