Cediranib, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

NCT00662506 · clinicaltrials.gov ↗

PHASE1,PHASE2

Phase

COMPLETED

Status

46

Enrollment

NIH

Sponsor class

Conditions

Adult Giant Cell Glioblastoma
Adult Glioblastoma
Adult Gliosarcoma

Interventions

DRUG: Cediranib Maleate
PROCEDURE: Diffusion Tensor Imaging
PROCEDURE: Diffusion Weighted Imaging
PROCEDURE: Dynamic Contrast-Enhanced Magnetic Resonance Imaging
RADIATION: Fludeoxyglucose F-18
RADIATION: Intensity-Modulated Radiation Therapy
OTHER: Laboratory Biomarker Analysis
PROCEDURE: Perfusion Magnetic Resonance Imaging
PROCEDURE: Positron Emission Tomography
DRUG: Temozolomide

Sponsor

National Cancer Institute (NCI)