# Clinical Study to Assess the Long-term Safety and Tolerability of ACT 064992 in Patients With Symptomatic Pulmonary Arterial Hypertension

> **NCT00667823** · PHASE3 · COMPLETED · sponsor: **Actelion** · enrollment: 550 (actual)

## Conditions studied

- Pulmonary Arterial Hypertension

## Interventions

- **DRUG:** Macitentan

## Key facts

- **NCT ID:** NCT00667823
- **Lead sponsor:** Actelion
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2008-10-17
- **Primary completion:** 2020-12-07
- **Final completion:** 2020-12-07
- **Target enrollment:** 550 (ACTUAL)
- **Last updated:** 2025-03-30


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00667823

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00667823, "Clinical Study to Assess the Long-term Safety and Tolerability of ACT 064992 in Patients With Symptomatic Pulmonary Arterial Hypertension". Retrieved via AI Analytics 2026-07-26 from https://api.ai-analytics.org/clinical/NCT00667823. Licensed CC0.

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