# A 72-week Randomized Clinical Trial Comparing the Safety and Efficacy of Three Initial Antiretroviral Regimens -GPO-VIR S (d4T/3TC/NVP) for 24 Weeks Followed by GPO-VIR Z (AZT/3TC/NVP) vs GPO-VIR Z vs TDF/FTC/NVP

> **NCT00669487** · PHASE3 · COMPLETED · sponsor: **SEARCH Research Foundation** · enrollment: 150 (actual)

## Conditions studied

- HIV Infections

## Interventions

- **DRUG:** AZT/3TC/NVP, AZT/D4T/NVP, Truvada/NVP
- **DRUG:** AZT/3TC/NVP, AZT/D4T/NVP, Truvada/NVP
- **DRUG:** AZT/3TC/NVP, AZT/D4T/NVP, Truvada/NVP

## Key facts

- **NCT ID:** NCT00669487
- **Lead sponsor:** SEARCH Research Foundation
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2008-04
- **Primary completion:** 2010-12
- **Final completion:** 2011-04
- **Target enrollment:** 150 (ACTUAL)
- **Last updated:** 2015-05-28

## Collaborators

- [object Object]
- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00669487

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00669487, "A 72-week Randomized Clinical Trial Comparing the Safety and Efficacy of Three Initial Antiretroviral Regimens -GPO-VIR S (d4T/3TC/NVP) for 24 Weeks Followed by GPO-VIR Z (AZT/3TC/NVP) vs GPO-VIR Z vs TDF/FTC/NVP". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT00669487. Licensed CC0.

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