# Safety and Efficacy Study of 4975 in Patients Undergoing Total Knee Replacement

> **NCT00681356** · PHASE3 · COMPLETED · sponsor: **Anesiva, Inc.** · enrollment: 214 (estimated)

## Conditions studied

- Total Knee Arthroplasty (Replacement)

## Interventions

- **DRUG:** 4975, 15 and 5 mg
- **DRUG:** Placebo Comparator
- **DRUG:** 4975 - 5 mg

## Key facts

- **NCT ID:** NCT00681356
- **Lead sponsor:** Anesiva, Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2007-09
- **Primary completion:** 2008-09
- **Final completion:** 2008-12
- **Target enrollment:** 214 (ESTIMATED)
- **Last updated:** 2009-05-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00681356

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00681356, "Safety and Efficacy Study of 4975 in Patients Undergoing Total Knee Replacement". Retrieved via AI Analytics 2026-07-18 from https://api.ai-analytics.org/clinical/NCT00681356. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*