# Calfactant for Direct Acute Respiratory Distress Syndrome

> **NCT00682500** · PHASE3 · TERMINATED · sponsor: **Pneuma Pharmaceuticals Incorporated** · enrollment: 332 (actual)

## Conditions studied

- Respiratory Distress Syndrome, Adult

## Interventions

- **DRUG:** Calfactant
- **DRUG:** Room Air (placebo)

## Key facts

- **NCT ID:** NCT00682500
- **Lead sponsor:** Pneuma Pharmaceuticals Incorporated
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2008-05
- **Primary completion:** 2010-12
- **Final completion:** 2011-02
- **Target enrollment:** 332 (ACTUAL)
- **Why stopped:** Expected mortality rates in placebo and treatment groups lower than predicted
- **Last updated:** 2012-07-24


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00682500

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00682500, "Calfactant for Direct Acute Respiratory Distress Syndrome". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT00682500. Licensed CC0.

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