# Observing Young Patients With Ependymoma Undergoing Standard Combination Chemotherapy

> **NCT00683319** · — · ACTIVE_NOT_RECRUITING · sponsor: **Children's Cancer and Leukaemia Group** · enrollment: 50 (estimated)

## Conditions studied

- Brain and Central Nervous System Tumors
- Cognitive/Functional Effects
- Long-term Effects Secondary to Cancer Therapy in Children
- Ototoxicity

## Interventions

- **DRUG:** carboplatin
- **DRUG:** cisplatin
- **DRUG:** cyclophosphamide
- **DRUG:** methotrexate
- **DRUG:** vincristine sulfate
- **PROCEDURE:** adjuvant therapy
- **PROCEDURE:** cognitive assessment
- **PROCEDURE:** magnetic resonance imaging
- **PROCEDURE:** magnetic resonance spectroscopic imaging
- **PROCEDURE:** quality-of-life assessment

## Key facts

- **NCT ID:** NCT00683319
- **Lead sponsor:** Children's Cancer and Leukaemia Group
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2008-04
- **Primary completion:** 2034-03
- **Final completion:** —
- **Target enrollment:** 50 (ESTIMATED)
- **Last updated:** 2013-09-20


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00683319

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00683319, "Observing Young Patients With Ependymoma Undergoing Standard Combination Chemotherapy". Retrieved via AI Analytics 2026-06-26 from https://api.ai-analytics.org/clinical/NCT00683319. Licensed CC0.

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