# Evaluation of Immune Memory to Twinrix or Comparator by Challenge Dose Administration 4 Years After Primary Vaccination

> **NCT00684671** · PHASE4 · COMPLETED · sponsor: **GlaxoSmithKline** · enrollment: 506 (actual)

## Conditions studied

- Hepatitis A
- Hepatitis B

## Interventions

- **BIOLOGICAL:** Twinrix
- **BIOLOGICAL:** Engerix-B
- **BIOLOGICAL:** Havrix
- **BIOLOGICAL:** HBVAXPRO
- **BIOLOGICAL:** Vaqta

## Key facts

- **NCT ID:** NCT00684671
- **Lead sponsor:** GlaxoSmithKline
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2008-05-26
- **Primary completion:** 2008-11-03
- **Final completion:** 2008-11-03
- **Target enrollment:** 506 (ACTUAL)
- **Last updated:** 2018-08-17


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00684671

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00684671, "Evaluation of Immune Memory to Twinrix or Comparator by Challenge Dose Administration 4 Years After Primary Vaccination". Retrieved via AI Analytics 2026-07-19 from https://api.ai-analytics.org/clinical/NCT00684671. Licensed CC0.

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