# Total Marrow Irradiation for Refractory Acute Leukemia

> **NCT00686556** · PHASE1 · COMPLETED · sponsor: **Masonic Cancer Center, University of Minnesota** · enrollment: 12 (actual)

## Conditions studied

- Acute Lymphoblastic Leukemia
- Myelodysplastic Syndrome
- Multiple Myeloma

## Interventions

- **DRUG:** cyclophosphamide
- **DRUG:** cyclosporine
- **DRUG:** Fludarabine
- **DRUG:** mycophenolate mofetil
- **RADIATION:** total marrow irradiation
- **PROCEDURE:** umbilical cord blood transplantation
- **BIOLOGICAL:** Granulocyte colony-stimulating factor
- **BIOLOGICAL:** HLA-matched related donor bone marrow

## Key facts

- **NCT ID:** NCT00686556
- **Lead sponsor:** Masonic Cancer Center, University of Minnesota
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2012-08
- **Primary completion:** 2016-11
- **Final completion:** 2016-12
- **Target enrollment:** 12 (ACTUAL)
- **Last updated:** 2017-12-05


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00686556

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00686556, "Total Marrow Irradiation for Refractory Acute Leukemia". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT00686556. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*