# TC-5214 as add-on the Treatment of Major Depressive Disorder

> **NCT00692445** · PHASE2 · COMPLETED · sponsor: **Targacept Inc.** · enrollment: 574 (actual)

## Conditions studied

- Major Depressive Disorder
- Depression

## Interventions

- **DRUG:** TC-5214 + citalopram
- **DRUG:** Placebo + citalopram

## Key facts

- **NCT ID:** NCT00692445
- **Lead sponsor:** Targacept Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2008-06
- **Primary completion:** 2009-05
- **Final completion:** 2009-07
- **Target enrollment:** 574 (ACTUAL)
- **Last updated:** 2013-06-21


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00692445

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00692445, "TC-5214 as add-on the Treatment of Major Depressive Disorder". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT00692445. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
