# Study to Assess the Safety and Tolerability of IV Tonapofylline in Subjects With Acute Decompensated Heart Failure (ADHF) and Renal Insufficiency

> **NCT00709865** · PHASE3 · COMPLETED · sponsor: **Biogen** · enrollment: 420 (actual)

## Conditions studied

- Renal Insufficiency
- Congestive Heart Failure

## Interventions

- **DRUG:** tonapofylline
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT00709865
- **Lead sponsor:** Biogen
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2008-07-31
- **Primary completion:** 2009-10-30
- **Final completion:** 2009-12-31
- **Target enrollment:** 420 (ACTUAL)
- **Last updated:** 2023-09-11


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00709865

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00709865, "Study to Assess the Safety and Tolerability of IV Tonapofylline in Subjects With Acute Decompensated Heart Failure (ADHF) and Renal Insufficiency". Retrieved via AI Analytics 2026-06-26 from https://api.ai-analytics.org/clinical/NCT00709865. Licensed CC0.

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