# Non-Pharmacologic Interventions to Relief Pain in Healthy Newborns Submitted to Vaccination to Hepatitis B

> **NCT00713986** · PHASE3 · COMPLETED · sponsor: **Federal University of São Paulo** · enrollment: 640 (actual)

## Conditions studied

- Pain
- Analgesia

## Interventions

- **PROCEDURE:** Water 2mL PO 2 minutes prior to intra-muscular injection
- **PROCEDURE:** skin-to-skin contact
- **PROCEDURE:** Glucose 25% 2 mL PO 2 minutes prior to injection
- **PROCEDURE:** neonates will receive skin-to-skin contact beginning 2 minutes after the intra-muscular injection and stopping 2 minutes afterwards.

## Key facts

- **NCT ID:** NCT00713986
- **Lead sponsor:** Federal University of São Paulo
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2006-03
- **Primary completion:** 2007-10
- **Final completion:** 2008-07
- **Target enrollment:** 640 (ACTUAL)
- **Last updated:** 2008-07-14


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00713986

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00713986, "Non-Pharmacologic Interventions to Relief Pain in Healthy Newborns Submitted to Vaccination to Hepatitis B". Retrieved via AI Analytics 2026-06-16 from https://api.ai-analytics.org/clinical/NCT00713986. Licensed CC0.

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