# Autologous Stem Cell Transplant for Neurologic Autoimmune Diseases

> **NCT00716066** · PHASE2 · ACTIVE_NOT_RECRUITING · sponsor: **Fred Hutchinson Cancer Center** · enrollment: 53 (actual)

## Conditions studied

- Autoimmune Disease
- Neurologic Autoimmune Disease
- Autologous Transplant Autoimmune
- Multiple Sclerosis Transplant
- MS Stem Cell Transplant
- Multiple Sclerosis Stem Cell Transplant
- Stiff Person Syndrome
- HCT for Neurologic Autoimmune Disorders
- CIDP Transplant
- Myasthenia Gravis Transplant
- Autoimmune Nervous System Disorder
- Central Nervous System Vasculitis
- Cerebellar Degeneration
- Chronic Inflammatory Demyelinating Polyneuropathy
- Lambert Eaton Myasthenic Syndrome
- Myasthenia Gravis
- Neuromyelitis Optica
- Opsoclonus Myoclonus Syndrome
- Rasmussen Subacute Encephalitis

## Interventions

- **BIOLOGICAL:** Anti-Thymocyte Globulin
- **PROCEDURE:** Autologous Hematopoietic Stem Cell Transplantation
- **DRUG:** Carmustine
- **DRUG:** Cytarabine
- **DRUG:** Etoposide
- **OTHER:** Laboratory Biomarker Analysis
- **DRUG:** Melphalan
- **PROCEDURE:** Peripheral Blood Stem Cell Transplantation
- **DRUG:** Prednisone
- **PROCEDURE:** Syngeneic Bone Marrow Transplantation

## Key facts

- **NCT ID:** NCT00716066
- **Lead sponsor:** Fred Hutchinson Cancer Center
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2008-06
- **Primary completion:** 2025-12-30
- **Final completion:** 2030-01-31
- **Target enrollment:** 53 (ACTUAL)
- **Last updated:** 2026-02-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00716066

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00716066, "Autologous Stem Cell Transplant for Neurologic Autoimmune Diseases". Retrieved via AI Analytics 2026-07-31 from https://api.ai-analytics.org/clinical/NCT00716066. Licensed CC0.

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