Dasatinib and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

NCT00720109 · clinicaltrials.gov ↗

PHASE2,PHASE3

Phase

COMPLETED

Status

63

Enrollment

NIH

Sponsor class

Conditions

Acute Lymphoblastic Leukemia
Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1
Childhood B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1

Interventions

DRUG: Asparaginase
DRUG: Cyclophosphamide
DRUG: Cytarabine
DRUG: Dasatinib
DRUG: Daunorubicin Hydrochloride
DRUG: Dexamethasone
DRUG: Etoposide
BIOLOGICAL: Filgrastim
DRUG: Hydrocortisone Sodium Succinate
DRUG: Ifosfamide
OTHER: Laboratory Biomarker Analysis
DRUG: Leucovorin Calcium
DRUG: Mercaptopurine
DRUG: Methotrexate
DRUG: Methylprednisolone
DRUG: Pegaspargase
DRUG: Prednisone
RADIATION: Radiation Therapy
DRUG: Vincristine Sulfate

Sponsor

National Cancer Institute (NCI)