# Prophylactic Probiotics in Premature Infants

> **NCT00727363** · PHASE3 · TERMINATED · sponsor: **Colombian Neonatal Research Network** · enrollment: 751 (actual)

## Conditions studied

- Death
- Nosocomial Infection

## Interventions

- **DIETARY_SUPPLEMENT:** Lactobacillus reuteri
- **DIETARY_SUPPLEMENT:** Placebo

## Key facts

- **NCT ID:** NCT00727363
- **Lead sponsor:** Colombian Neonatal Research Network
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2008-08
- **Primary completion:** 2011-06
- **Final completion:** 2011-08
- **Target enrollment:** 751 (ACTUAL)
- **Why stopped:** We are underpowered to find a difference in the primary outcome.
- **Last updated:** 2011-06-22

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00727363

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00727363, "Prophylactic Probiotics in Premature Infants". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT00727363. Licensed CC0.

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