# Effects of Chemotherapy on the Brain in Women With Newly Diagnosed Early-Stage Breast Cancer

> **NCT00755313** · — · COMPLETED · sponsor: **University of California, San Francisco** · enrollment: 81 (actual)

## Conditions studied

- Breast Cancer
- Chemotherapeutic Agent Toxicity
- Cognitive/Functional Effects
- Fatigue
- Long-term Effects Secondary to Cancer Therapy in Adults
- Neurotoxicity
- Psychosocial Effects of Cancer and Its Treatment

## Interventions

- **BIOLOGICAL:** trastuzumab
- **DRUG:** aromatase inhibition therapy
- **DRUG:** carboplatin
- **DRUG:** cyclophosphamide
- **DRUG:** docetaxel
- **DRUG:** doxorubicin hydrochloride
- **OTHER:** metabolic assessment
- **OTHER:** questionnaire administration
- **OTHER:** study of socioeconomic and demographic variables
- **PROCEDURE:** cognitive assessment
- **PROCEDURE:** positron emission tomography
- **RADIATION:** fludeoxyglucose F 18

## Key facts

- **NCT ID:** NCT00755313
- **Lead sponsor:** University of California, San Francisco
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** COMPLETED
- **Start date:** 2007-05
- **Primary completion:** 2012-09
- **Final completion:** 2014-06-06
- **Target enrollment:** 81 (ACTUAL)
- **Last updated:** 2017-11-24

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00755313

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00755313, "Effects of Chemotherapy on the Brain in Women With Newly Diagnosed Early-Stage Breast Cancer". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT00755313. Licensed CC0.

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