# Study of the Efficacy of Losartan on Aortic Dilatation in Patients With Marfan Syndrome

> **NCT00763893** · PHASE3 · TERMINATED · sponsor: **Assistance Publique - Hôpitaux de Paris** · enrollment: 303 (actual)

## Conditions studied

- Marfan Syndrome

## Interventions

- **DRUG:** placebo
- **DRUG:** Losartan

## Key facts

- **NCT ID:** NCT00763893
- **Lead sponsor:** Assistance Publique - Hôpitaux de Paris
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2008-09
- **Primary completion:** 2014-01
- **Final completion:** 2014-12
- **Target enrollment:** 303 (ACTUAL)
- **Why stopped:** A similar publication has been released, suggesting a beneficial effect of sartans, and only 15 patients remained to be seen for their visit at 36 months.
- **Last updated:** 2015-11-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00763893

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00763893, "Study of the Efficacy of Losartan on Aortic Dilatation in Patients With Marfan Syndrome". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT00763893. Licensed CC0.

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