# ABT-888, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

> **NCT00770471** · PHASE1 · COMPLETED · sponsor: **Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins** · enrollment: 24 (actual)

## Conditions studied

- Brain and Central Nervous System Tumors

## Interventions

- **DRUG:** temozolomide
- **DRUG:** veliparib
- **GENETIC:** DNA methylation analysis
- **GENETIC:** gene expression analysis
- **GENETIC:** mutation analysis
- **GENETIC:** proteomic profiling
- **OTHER:** high performance liquid chromatography
- **OTHER:** immunoenzyme technique
- **OTHER:** laboratory biomarker analysis
- **OTHER:** mass spectrometry
- **OTHER:** pharmacogenomic studies
- **OTHER:** pharmacological study
- **PROCEDURE:** adjuvant therapy
- **RADIATION:** radiation therapy

## Key facts

- **NCT ID:** NCT00770471
- **Lead sponsor:** Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2009-07-13
- **Primary completion:** 2012-03-01
- **Final completion:** 2012-03-01
- **Target enrollment:** 24 (ACTUAL)
- **Last updated:** 2018-06-27

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00770471

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00770471, "ABT-888, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT00770471. Licensed CC0.

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