# Chemotherapy and Radiation Therapy in Treating Patients With Stage II or Stage III Bladder Cancer That Was Removed by Surgery

> **NCT00777491** · PHASE2 · COMPLETED · sponsor: **Radiation Therapy Oncology Group** · enrollment: 70 (actual)

## Conditions studied

- Bladder Cancer

## Interventions

- **DRUG:** induction cisplatin
- **DRUG:** induction 5-fluorouracil
- **DRUG:** induction gemcitabine
- **RADIATION:** Induction BID radiation therapy
- **RADIATION:** Induction QD radiation therapy
- **RADIATION:** Consolidation BID radiation therapy
- **RADIATION:** Consolidation QD radiation therapy
- **DRUG:** consolidation gemcitabine
- **DRUG:** consolidation 5-fluorouracil
- **DRUG:** consolidation cisplatin
- **PROCEDURE:** radical cystectomy
- **PROCEDURE:** Post-Induction Chemoradiotherapy Endoscopic Response Evaluation
- **DRUG:** adjuvant gemcitabine
- **DRUG:** adjuvant cisplatin

## Key facts

- **NCT ID:** NCT00777491
- **Lead sponsor:** Radiation Therapy Oncology Group
- **Sponsor class:** NETWORK
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2008-12
- **Primary completion:** 2018-02-18
- **Final completion:** 2022-05-20
- **Target enrollment:** 70 (ACTUAL)
- **Last updated:** 2022-06-15

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00777491

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00777491, "Chemotherapy and Radiation Therapy in Treating Patients With Stage II or Stage III Bladder Cancer That Was Removed by Surgery". Retrieved via AI Analytics 2026-07-26 from https://api.ai-analytics.org/clinical/NCT00777491. Licensed CC0.

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