# TNF-alpha Antagonists for AECOPD: A Randomized, Double-Blind, Placebo-Controlled Pilot Trial

> **NCT00789997** · PHASE2,PHASE3 · COMPLETED · sponsor: **Ottawa Hospital Research Institute** · enrollment: 81 (actual)

## Conditions studied

- COPD Exacerbation

## Interventions

- **DRUG:** Prednisone
- **DRUG:** Etanercept
- **DRUG:** levofloxacin

## Key facts

- **NCT ID:** NCT00789997
- **Lead sponsor:** Ottawa Hospital Research Institute
- **Sponsor class:** OTHER
- **Phase:** PHASE2,PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2008-11
- **Primary completion:** 2011-08
- **Final completion:** 2011-10
- **Target enrollment:** 81 (ACTUAL)
- **Last updated:** 2016-04-11


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00789997

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00789997, "TNF-alpha Antagonists for AECOPD: A Randomized, Double-Blind, Placebo-Controlled Pilot Trial". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT00789997. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
