# A Study of Intrathecal Enzyme Therapy for Cognitive Decline in MPS I

> **NCT00852358** · NA · COMPLETED · sponsor: **Patricia I. Dickson, M.D.** · enrollment: 9 (actual)

## Conditions studied

- Cognitive Decline
- Mucopolysaccharidosis I
- Hurler-Scheie Syndrome
- Scheie Syndrome
- Lysosomal Storage Disease

## Interventions

- **DRUG:** laronidase

## Key facts

- **NCT ID:** NCT00852358
- **Lead sponsor:** Patricia I. Dickson, M.D.
- **Sponsor class:** INDIV
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2009-06
- **Primary completion:** 2015-04
- **Final completion:** 2015-04
- **Target enrollment:** 9 (ACTUAL)
- **Last updated:** 2016-01-26

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00852358

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00852358, "A Study of Intrathecal Enzyme Therapy for Cognitive Decline in MPS I". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT00852358. Licensed CC0.

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