# rhBMP-2 Versus Autograft in Critical Size Tibial Defects

> **NCT00853489** · PHASE4 · TERMINATED · sponsor: **St. Louis University** · enrollment: 33 (actual)

## Conditions studied

- Tibial Fractures

## Interventions

- **DEVICE:** recombinant bone morphogenetic protein 2
- **PROCEDURE:** Autogenous iliac crest bone graft

## Key facts

- **NCT ID:** NCT00853489
- **Lead sponsor:** St. Louis University
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2011-08
- **Primary completion:** 2017-02-17
- **Final completion:** 2017-02-17
- **Target enrollment:** 33 (ACTUAL)
- **Why stopped:** Enrollment too slow
- **Last updated:** 2018-10-25

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00853489

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00853489, "rhBMP-2 Versus Autograft in Critical Size Tibial Defects". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT00853489. Licensed CC0.

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