# Efficacy and Safety of Memantine in Moderate to Severe Alzheimer's Disease

> **NCT00857649** · PHASE3 · TERMINATED · sponsor: **H. Lundbeck A/S** · enrollment: 369 (actual)

## Conditions studied

- Alzheimer's Disease

## Interventions

- **DRUG:** Memantine
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT00857649
- **Lead sponsor:** H. Lundbeck A/S
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2003-12
- **Primary completion:** 2010-04
- **Final completion:** 2010-09
- **Target enrollment:** 369 (ACTUAL)
- **Last updated:** 2013-12-05


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00857649

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00857649, "Efficacy and Safety of Memantine in Moderate to Severe Alzheimer's Disease". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT00857649. Licensed CC0.

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