# High-dose Chemotherapy With Transplantation of Gene-modified Haematopoietic Stem Cells for HIV-positive Patients With Malignant Diseases Indicating an HSCT

> **NCT00858793** · PHASE1,PHASE2 · TERMINATED · sponsor: **Universitätsklinikum Hamburg-Eppendorf** · enrollment: 5 (actual)

## Conditions studied

- AIDS-related Lymphoma
- HIV Infections

## Interventions

- **PROCEDURE:** PBSC-M87o, Gene (M87o)-modified, CD34+ peripheral blood progenitor cells (PBSC)

## Key facts

- **NCT ID:** NCT00858793
- **Lead sponsor:** Universitätsklinikum Hamburg-Eppendorf
- **Sponsor class:** OTHER
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2008-11-28
- **Primary completion:** 2016-08-31
- **Final completion:** 2016-08-31
- **Target enrollment:** 5 (ACTUAL)
- **Why stopped:** A leukaemia case was reported in patient treated with a similar vector. For safety risk we stopped recruitment
- **Last updated:** 2022-09-08


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00858793

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00858793, "High-dose Chemotherapy With Transplantation of Gene-modified Haematopoietic Stem Cells for HIV-positive Patients With Malignant Diseases Indicating an HSCT". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT00858793. Licensed CC0.

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