# Ursodiol, Combination Chemotherapy, and Bevacizumab in Treating Patients With Stage IV Colorectal Cancer

> **NCT00873275** · PHASE1 · COMPLETED · sponsor: **City of Hope Medical Center** · enrollment: 11 (actual)

## Conditions studied

- Colorectal Cancer

## Interventions

- **BIOLOGICAL:** bevacizumab
- **DRUG:** FOLFOX regimen
- **DRUG:** fluorouracil
- **DRUG:** leucovorin calcium
- **DRUG:** oxaliplatin
- **DRUG:** ursodiol
- **GENETIC:** RNA analysis
- **GENETIC:** gene expression analysis
- **GENETIC:** polymerase chain reaction
- **GENETIC:** western blotting
- **OTHER:** immunohistochemistry staining method
- **OTHER:** laboratory biomarker analysis
- **OTHER:** pharmacological study
- **PROCEDURE:** positron emission tomography (PET)

## Key facts

- **NCT ID:** NCT00873275
- **Lead sponsor:** City of Hope Medical Center
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2009-03-11
- **Primary completion:** 2012-09-25
- **Final completion:** 2025-02-26
- **Target enrollment:** 11 (ACTUAL)
- **Last updated:** 2025-06-22

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00873275

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00873275, "Ursodiol, Combination Chemotherapy, and Bevacizumab in Treating Patients With Stage IV Colorectal Cancer". Retrieved via AI Analytics 2026-06-23 from https://api.ai-analytics.org/clinical/NCT00873275. Licensed CC0.

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