# International, Multicenter, Open-Label and Randomized Withdrawal Study of Oral Lixivaptan in Heart Failure Patients With Chronic Hyponatremia

> **NCT00876876** · PHASE3 · WITHDRAWN · sponsor: **CardioKine Inc.** · enrollment: 300 (estimated)

## Conditions studied

- Hypervolemic Hyponatremia

## Interventions

- **DRUG:** Lixivaptan

## Key facts

- **NCT ID:** NCT00876876
- **Lead sponsor:** CardioKine Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** WITHDRAWN
- **Start date:** 2009-07
- **Primary completion:** 2010-08
- **Final completion:** 2010-12
- **Target enrollment:** 300 (ESTIMATED)
- **Why stopped:** Created Extension study - This study was no longer feasible
- **Last updated:** 2010-11-23

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00876876

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00876876, "International, Multicenter, Open-Label and Randomized Withdrawal Study of Oral Lixivaptan in Heart Failure Patients With Chronic Hyponatremia". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT00876876. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*