# Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of AZD1386 in Patients With Osteoarthritis (OA) of the Knee

> **NCT00878501** · PHASE2 · TERMINATED · sponsor: **AstraZeneca** · enrollment: 241 (actual)

## Conditions studied

- Pain

## Interventions

- **DRUG:** AZD1386
- **DRUG:** AZD1386
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT00878501
- **Lead sponsor:** AstraZeneca
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2009-03
- **Primary completion:** 2009-07
- **Final completion:** 2009-07
- **Target enrollment:** 241 (ACTUAL)
- **Why stopped:** The study was terminated after the planned interim analysis.
- **Last updated:** 2012-06-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00878501

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00878501, "Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of AZD1386 in Patients With Osteoarthritis (OA) of the Knee". Retrieved via AI Analytics 2026-06-05 from https://api.ai-analytics.org/clinical/NCT00878501. Licensed CC0.

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