# Radiation Therapy With Concomitant and Adjuvant Temozolomide Versus Radiation Therapy With Adjuvant PCV Chemotherapy in Patients With Anaplastic Glioma or Low Grade Glioma

> **NCT00887146** · PHASE3 · ACTIVE_NOT_RECRUITING · sponsor: **Alliance for Clinical Trials in Oncology** · enrollment: 305 (actual)

## Conditions studied

- Brain and Central Nervous System Tumors

## Interventions

- **DRUG:** concomitant temozolomide (TMZ)
- **RADIATION:** radiotherapy
- **DRUG:** procarbazine
- **DRUG:** adjuvant temozolomide (TMZ)
- **DRUG:** CCNU
- **DRUG:** vincristine

## Key facts

- **NCT ID:** NCT00887146
- **Lead sponsor:** Alliance for Clinical Trials in Oncology
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2009-09
- **Primary completion:** 2029-10-31
- **Final completion:** 2029-10-31
- **Target enrollment:** 305 (ACTUAL)
- **Last updated:** 2026-01-22

## Collaborators

- [object Object]
- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00887146

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00887146, "Radiation Therapy With Concomitant and Adjuvant Temozolomide Versus Radiation Therapy With Adjuvant PCV Chemotherapy in Patients With Anaplastic Glioma or Low Grade Glioma". Retrieved via AI Analytics 2026-09-07 from https://api.ai-analytics.org/clinical/NCT00887146. Licensed CC0.

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