Phase 2 Study of Autologous Followed by Nonmyeloablative Allogeneic Transplantation Using TLI & ATG

Conditions

• Transplantation, Homologous
• Transplantation, Autologous
• Multiple Myeloma
• Blood and Marrow Transplant (BMT)

Interventions

• PROCEDURE: Autologous peripheral blood stem cells (auto-PBSC) transplantation
• PROCEDURE: Allogeneic peripheral blood stem cells (allo-PBSC) transplantation
• DRUG: Filgrastim
• DRUG: Cyclophosphamide
• DRUG: Melphalan
• DRUG: Cyclosporine
• RADIATION: Total lymphoid irradiation
• BIOLOGICAL: Rabbit anti-thymocyte globulin
• DRUG: Mycophenolate Mofetil 250mg
• DRUG: Solumedrol
• DRUG: Diphenhydramine
• DRUG: Acetaminophen
• DRUG: Hydrocortisone

Sponsor

Stanford University