# Resistance to Methotrexate in Patients With Acute Lymphoblastic Leukemia in Relapse or Remission

> **NCT00899899** · — · COMPLETED · sponsor: **Children's Oncology Group** · enrollment: 135 (actual)

## Conditions studied

- Leukemia

## Interventions

- **GENETIC:** microarray analysis
- **GENETIC:** reverse transcriptase-polymerase chain reaction
- **OTHER:** laboratory biomarker analysis

## Key facts

- **NCT ID:** NCT00899899
- **Lead sponsor:** Children's Oncology Group
- **Sponsor class:** NETWORK
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** COMPLETED
- **Start date:** 1998-06
- **Primary completion:** 2005-03
- **Final completion:** 2006-04
- **Target enrollment:** 135 (ACTUAL)
- **Last updated:** 2015-09-30

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00899899

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00899899, "Resistance to Methotrexate in Patients With Acute Lymphoblastic Leukemia in Relapse or Remission". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT00899899. Licensed CC0.

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