# Oral Metolazone and Intermittent Intravenous Furosemide Versus Continuous Infusion Furosemide in Acute Heart Failure

> **NCT00904488** · PHASE4 · TERMINATED · sponsor: **University of North Carolina, Chapel Hill** · enrollment: 11 (actual)

## Conditions studied

- Acute Decompensated Heart Failure

## Interventions

- **DRUG:** Addition of oral Metolazone
- **DRUG:** Furosemide dose escalation

## Key facts

- **NCT ID:** NCT00904488
- **Lead sponsor:** University of North Carolina, Chapel Hill
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2008-10
- **Primary completion:** 2016-05-28
- **Final completion:** 2017-11-14
- **Target enrollment:** 11 (ACTUAL)
- **Why stopped:** Difficult recruitment
- **Last updated:** 2018-03-13

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00904488

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00904488, "Oral Metolazone and Intermittent Intravenous Furosemide Versus Continuous Infusion Furosemide in Acute Heart Failure". Retrieved via AI Analytics 2026-09-04 from https://api.ai-analytics.org/clinical/NCT00904488. Licensed CC0.

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