# Role of Nitric Oxide in Optic Nerve Head Blood Flow Regulation During Experimental Increase of Intraocular Pressure in Healthy Humans

> **NCT00914394** · NA · TERMINATED · sponsor: **Medical University of Vienna** · enrollment: 12 (actual)

## Conditions studied

- Healthy

## Interventions

- **DRUG:** NG-monomethyl-L-arginine (L-NMMA)
- **DRUG:** Phenylephrine
- **DRUG:** Physiological saline solution (as placebo)
- **DEVICE:** Laser Doppler Flowmetry
- **DEVICE:** Goldmann applanation tonometer
- **DEVICE:** Suction cup

## Key facts

- **NCT ID:** NCT00914394
- **Lead sponsor:** Medical University of Vienna
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2010-10
- **Primary completion:** 2011-07
- **Final completion:** —
- **Target enrollment:** 12 (ACTUAL)
- **Last updated:** 2014-11-14


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00914394

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00914394, "Role of Nitric Oxide in Optic Nerve Head Blood Flow Regulation During Experimental Increase of Intraocular Pressure in Healthy Humans". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT00914394. Licensed CC0.

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