# Role of Endothelin-1 in Optic Nerve Head Blood Flow Regulation During Isometric Exercise in Healthy Humans

> **NCT00915070** · NA · COMPLETED · sponsor: **Medical University of Vienna** · enrollment: 16 (actual)

## Conditions studied

- Healthy

## Interventions

- **DRUG:** BQ-123
- **DRUG:** Physiological saline solution
- **DEVICE:** Laser Doppler Flowmetry
- **DEVICE:** Goldmann Applanation Tonometer
- **OTHER:** squatting

## Key facts

- **NCT ID:** NCT00915070
- **Lead sponsor:** Medical University of Vienna
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2010-10
- **Primary completion:** 2011-05
- **Final completion:** 2011-12
- **Target enrollment:** 16 (ACTUAL)
- **Last updated:** 2012-08-10


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00915070

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00915070, "Role of Endothelin-1 in Optic Nerve Head Blood Flow Regulation During Isometric Exercise in Healthy Humans". Retrieved via AI Analytics 2026-06-23 from https://api.ai-analytics.org/clinical/NCT00915070. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*