# Pilot Study of Reduced Intensity Haematopoietic Stem Cell Transplantation in Patients With Poor Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukaemia (AML) Utilising Conditioning With Fludarabine, Busulphan and Thymoglobulin

> **NCT00915811** · PHASE2 · TERMINATED · sponsor: **King's College Hospital NHS Trust** · enrollment: 20 (estimated)

## Conditions studied

- Myelodysplastic Syndromes
- Leukemia, Myeloid, Acute

## Interventions

- **DRUG:** Fludarabine
- **DRUG:** Busulphan
- **DRUG:** Thymoglobuline (Anti-thymocyte globulin [rabbit]) - Genzyme
- **PROCEDURE:** Haematopoietic stem cell infusion

## Key facts

- **NCT ID:** NCT00915811
- **Lead sponsor:** King's College Hospital NHS Trust
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2007-06
- **Primary completion:** 2011-06
- **Final completion:** 2011-06
- **Target enrollment:** 20 (ESTIMATED)
- **Why stopped:** FB ATG is now a standard for sib allo MDS patients
- **Last updated:** 2011-08-17


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00915811

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00915811, "Pilot Study of Reduced Intensity Haematopoietic Stem Cell Transplantation in Patients With Poor Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukaemia (AML) Utilising Conditioning With Fludarabine, Busulphan and Thymoglobulin". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT00915811. Licensed CC0.

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