# Fat Mediated Modulation of Reproductive and Endocrine Function in Young Athletes

> **NCT00946192** · PHASE3 · COMPLETED · sponsor: **Massachusetts General Hospital** · enrollment: 121 (actual)

## Conditions studied

- Exercise-related Amenorrhea

## Interventions

- **DRUG:** Transdermal 17Beta-estradiol, progesterone
- **DRUG:** Ethinyl Estradiol + Desogestrel
- **DIETARY_SUPPLEMENT:** Sham Comparator

## Key facts

- **NCT ID:** NCT00946192
- **Lead sponsor:** Massachusetts General Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2009-05
- **Primary completion:** 2020-02
- **Final completion:** 2021-04
- **Target enrollment:** 121 (ACTUAL)
- **Last updated:** 2021-06-11

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00946192

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00946192, "Fat Mediated Modulation of Reproductive and Endocrine Function in Young Athletes". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT00946192. Licensed CC0.

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