# A Comparison of the Analgesic Efficacy and Safety of Once Daily Tramadol HCl / Contramid® Tablets to Twice Daily Tramadol HCl (SR) for the Treatment of Osteoarthritis of the Knee

> **NCT00950651** · PHASE3 · COMPLETED · sponsor: **Labopharm Inc.** · enrollment: 431 (actual)

## Conditions studied

- Osteoarthritis, Knee
- Pain

## Interventions

- **DRUG:** Tramadol HCl Contramid® Once A Day
- **DRUG:** Tramadol HCl Twice a day

## Key facts

- **NCT ID:** NCT00950651
- **Lead sponsor:** Labopharm Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2002-03
- **Primary completion:** 2002-11
- **Final completion:** 2002-11
- **Target enrollment:** 431 (ACTUAL)
- **Last updated:** 2012-04-30


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00950651

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00950651, "A Comparison of the Analgesic Efficacy and Safety of Once Daily Tramadol HCl / Contramid® Tablets to Twice Daily Tramadol HCl (SR) for the Treatment of Osteoarthritis of the Knee". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT00950651. Licensed CC0.

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