# Seroquel Alone Versus Seroquel With an SSRI for Depression With Psychotic Symptoms

> **NCT00955474** · PHASE4 · TERMINATED · sponsor: **Massachusetts General Hospital** · enrollment: 32 (actual)

## Conditions studied

- Major Depressive Disorder With Psychotic Features

## Interventions

- **DRUG:** Quetiapine
- **DRUG:** escitalopram
- **DRUG:** Sertraline
- **DRUG:** Citalopram

## Key facts

- **NCT ID:** NCT00955474
- **Lead sponsor:** Massachusetts General Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2008-09
- **Primary completion:** 2013-01
- **Final completion:** 2013-01
- **Target enrollment:** 32 (ACTUAL)
- **Why stopped:** AstraZeneca halted funding; patent expired for Seroquel (Quetiapine) in 2012
- **Last updated:** 2017-04-20


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00955474

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00955474, "Seroquel Alone Versus Seroquel With an SSRI for Depression With Psychotic Symptoms". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT00955474. Licensed CC0.

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