# Safety and Efficacy Study of Sirolimus in Complicated Vascular Anomalies

> **NCT00975819** · PHASE2 · COMPLETED · sponsor: **Denise Martin Adams** · enrollment: 61 (actual)

## Conditions studied

- Kaposiform Hemangioendotheliomas
- Tufted Angioma
- Capillary Venous Lymphatic Malformation
- Venous Lymphatic Malformation
- Microcystic Lymphatic Malformation
- Mucocutaneous Lymphangiomatosis and Thrombocytopenia
- Capillary Lymphatic Arterial Venous Malformations
- PTEN Overgrowth Syndrome With Vascular Anomaly
- Lymphangiectasia Syndromes

## Interventions

- **DRUG:** sirolimus

## Key facts

- **NCT ID:** NCT00975819
- **Lead sponsor:** Denise Martin Adams
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2009-10
- **Primary completion:** 2014-03
- **Final completion:** 2020-10
- **Target enrollment:** 61 (ACTUAL)
- **Last updated:** 2026-01-06

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00975819

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00975819, "Safety and Efficacy Study of Sirolimus in Complicated Vascular Anomalies". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT00975819. Licensed CC0.

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