# Study of Tumor Tissue Testing in Selecting Treatment for Patients With Metastatic or Locally Advanced Colorectal Cancer

> **NCT00975897** · PHASE2,PHASE3 · COMPLETED · sponsor: **Medical Research Council** · enrollment: 3240 (estimated)

## Conditions studied

- Colorectal Cancer

## Interventions

- **BIOLOGICAL:** bevacizumab
- **BIOLOGICAL:** cetuximab
- **DRUG:** fluorouracil
- **DRUG:** irinotecan hydrochloride
- **DRUG:** leucovorin calcium
- **DRUG:** oxaliplatin
- **GENETIC:** RNA analysis
- **GENETIC:** cytogenetic analysis
- **GENETIC:** fluorescence in situ hybridization
- **GENETIC:** gene expression analysis
- **GENETIC:** mutation analysis
- **GENETIC:** protein expression analysis
- **OTHER:** diagnostic laboratory biomarker analysis
- **OTHER:** immunohistochemistry staining method
- **OTHER:** questionnaire administration
- **PROCEDURE:** cognitive assessment

## Key facts

- **NCT ID:** NCT00975897
- **Lead sponsor:** Medical Research Council
- **Sponsor class:** OTHER_GOV
- **Phase:** PHASE2,PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2009-07
- **Primary completion:** 2010-08
- **Final completion:** 2012-12
- **Target enrollment:** 3240 (ESTIMATED)
- **Last updated:** 2013-12-19


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00975897

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00975897, "Study of Tumor Tissue Testing in Selecting Treatment for Patients With Metastatic or Locally Advanced Colorectal Cancer". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT00975897. Licensed CC0.

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