# Safety and Efficacy of Carboxymethylcellulose for Ocular Surface Integrity in Symptomatic Dry Eye

> **NCT00987727** · PHASE4 · COMPLETED · sponsor: **Allergan** · enrollment: 82 (actual)

## Conditions studied

- Dry Eye Syndromes
- Keratoconjunctivitis Sicca

## Interventions

- **DRUG:** carboxymethylcellulose 0.5% , glycerin 0.9% (OPTIVE® MD)
- **DRUG:** sodium hyaluronate 0.18% (VISMED® Multi)

## Key facts

- **NCT ID:** NCT00987727
- **Lead sponsor:** Allergan
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2009-11
- **Primary completion:** 2010-07
- **Final completion:** 2010-09
- **Target enrollment:** 82 (ACTUAL)
- **Last updated:** 2011-09-21


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00987727

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00987727, "Safety and Efficacy of Carboxymethylcellulose for Ocular Surface Integrity in Symptomatic Dry Eye". Retrieved via AI Analytics 2026-06-12 from https://api.ai-analytics.org/clinical/NCT00987727. Licensed CC0.

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