# Proof Of Mechanism Study To Determine Efficacy Of PF-04455242 In Blocking Spiradoline (PF-00345768) Stimulated Prolactin Release

> **NCT00988949** · PHASE1 · COMPLETED · sponsor: **Pfizer** · enrollment: 24 (actual)

## Conditions studied

- Bipolar Depression

## Interventions

- **DRUG:** PF-04455242
- **DRUG:** spiradoline
- **OTHER:** Placebo
- **DRUG:** spiradoline
- **DRUG:** PF-04455242
- **DRUG:** spiradoline

## Key facts

- **NCT ID:** NCT00988949
- **Lead sponsor:** Pfizer
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2009-11
- **Primary completion:** 2009-12
- **Final completion:** 2009-12
- **Target enrollment:** 24 (ACTUAL)
- **Last updated:** 2010-01-07


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00988949

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00988949, "Proof Of Mechanism Study To Determine Efficacy Of PF-04455242 In Blocking Spiradoline (PF-00345768) Stimulated Prolactin Release". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT00988949. Licensed CC0.

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