A Randomized Phase II Trial of Vandetanib (ZD6474) in Combination With Carboplatin Versus Carboplatin Alone Followed by Vandetanib Alone in Adults With Recurrent High-Grade Gliomas

NCT00995007 · clinicaltrials.gov ↗

PHASE2

Phase

COMPLETED

Status

112

Enrollment

NIH

Sponsor class

Conditions

Glioblastoma Multiforme
Gliosarcoma
Anaplastic Astrocytoma
Anaplastic Oligodendroglioma
Anaplastic Mixed Oligoastrocytoma

Interventions

DRUG: ZD6474 (Vandetanib)
DRUG: Carboplatin

Sponsor

National Cancer Institute (NCI)