# The Effects of Corticosteroids, Glucose Control, and Depth-of-Anesthesia on Perioperative Inflammation and Morbidity From Major Non-cardiac Surgery (Dexamethasone, Light Anesthesia and Tight Glucose Control (DeLiT Trial))

> **NCT00995501** · NA · TERMINATED · sponsor: **d sessler** · enrollment: 381 (actual)

## Conditions studied

- Inflammation
- Perioperative Morbidity

## Interventions

- **DRUG:** Dexamethasone Sodium Sulfate
- **DRUG:** Insulin
- **DRUG:** anesthesia management
- **OTHER:** Dexamethasone - placebo
- **OTHER:** Insulin - Placebo
- **OTHER:** Anesthesia management -Placebo

## Key facts

- **NCT ID:** NCT00995501
- **Lead sponsor:** d sessler
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2007-01
- **Primary completion:** 2015-12
- **Final completion:** 2015-12
- **Target enrollment:** 381 (ACTUAL)
- **Why stopped:** Per interim analysis, for futility.
- **Last updated:** 2017-04-25


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00995501

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00995501, "The Effects of Corticosteroids, Glucose Control, and Depth-of-Anesthesia on Perioperative Inflammation and Morbidity From Major Non-cardiac Surgery (Dexamethasone, Light Anesthesia and Tight Glucose Control (DeLiT Trial))". Retrieved via AI Analytics 2026-06-05 from https://api.ai-analytics.org/clinical/NCT00995501. Licensed CC0.

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