# Neural Substrates in Nicotine Withdrawal

> **NCT01001520** · PHASE2 · COMPLETED · sponsor: **University of Pennsylvania** · enrollment: 218 (actual)

## Conditions studied

- Tobacco Use Disorder

## Interventions

- **DRUG:** Tolcapone
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT01001520
- **Lead sponsor:** University of Pennsylvania
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2010-01
- **Primary completion:** 2012-10
- **Final completion:** 2012-10
- **Target enrollment:** 218 (ACTUAL)
- **Last updated:** 2014-07-02

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01001520

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01001520, "Neural Substrates in Nicotine Withdrawal". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT01001520. Licensed CC0.

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