# Autologous Peripheral Blood Stem Cell Transplant Followed by Donor Bone Marrow Transplant in Treating Patients With High-Risk Hodgkin Lymphoma, Non-Hodgkin Lymphoma, Multiple Myeloma, or Chronic Lymphocytic Leukemia

> **NCT01008462** · PHASE2 · COMPLETED · sponsor: **Fred Hutchinson Cancer Center** · enrollment: 16 (actual)

## Conditions studied

- B-Cell Prolymphocytic Leukemia
- Hypodiploidy
- Loss of Chromosome 17p
- Plasma Cell Leukemia
- Progression of Multiple Myeloma or Plasma Cell Leukemia
- Recurrent Adult Hodgkin Lymphoma
- Recurrent Adult Non-Hodgkin Lymphoma
- Recurrent Childhood Hodgkin Lymphoma
- Recurrent Childhood Non-Hodgkin Lymphoma
- Recurrent Chronic Lymphocytic Leukemia
- Recurrent Plasma Cell Myeloma
- Recurrent Small Lymphocytic Lymphoma
- Refractory Childhood Hodgkin Lymphoma
- Refractory Chronic Lymphocytic Leukemia
- Refractory Non-Hodgkin Lymphoma
- Refractory Plasma Cell Myeloma
- Refractory Small Lymphocytic Lymphoma
- t(14;16)
- t(4;14)
- T-Cell Prolymphocytic Leukemia
- Waldenstrom Macroglobulinemia

## Interventions

- **PROCEDURE:** Allogeneic Bone Marrow Transplantation
- **PROCEDURE:** Allogeneic Hematopoietic Stem Cell Transplantation
- **PROCEDURE:** Autologous Hematopoietic Stem Cell Transplantation
- **PROCEDURE:** Autologous-Allogeneic Tandem Hematopoietic Stem Cell Transplantation
- **DRUG:** Carmustine
- **DRUG:** Cyclophosphamide
- **DRUG:** Cytarabine
- **DRUG:** Etoposide
- **DRUG:** Fludarabine Phosphate
- **OTHER:** Laboratory Biomarker Analysis
- **DRUG:** Melphalan
- **DRUG:** Mycophenolate Mofetil
- **PROCEDURE:** Peripheral Blood Stem Cell Transplantation
- **DRUG:** Tacrolimus
- **RADIATION:** Total-Body Irradiation

## Key facts

- **NCT ID:** NCT01008462
- **Lead sponsor:** Fred Hutchinson Cancer Center
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2010-03-18
- **Primary completion:** 2018-06-30
- **Final completion:** 2018-06-30
- **Target enrollment:** 16 (ACTUAL)
- **Last updated:** 2019-06-11

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01008462

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01008462, "Autologous Peripheral Blood Stem Cell Transplant Followed by Donor Bone Marrow Transplant in Treating Patients With High-Risk Hodgkin Lymphoma, Non-Hodgkin Lymphoma, Multiple Myeloma, or Chronic Lymphocytic Leukemia". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT01008462. Licensed CC0.

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