# Composite Variability Index Versus Bispectral Index (BIS)

> **NCT01053611** · NA · COMPLETED · sponsor: **University Medical Center Groningen** · enrollment: 140 (actual)

## Conditions studied

- Sedation During

## Interventions

- **DRUG:** propofol + remifentanil 0 ng/ml
- **DRUG:** propofol + remifentanil 2 ng/ml
- **DRUG:** propofol + remifentanil 4 ng/ml
- **DRUG:** propofol + remifentanil 6 ng/ml
- **DRUG:** propofol + remifentanil 0 ng/ml
- **DRUG:** propofol + remifentanil 2 ng/ml
- **DRUG:** propofol + remifentanil 6 ng/ml
- **DRUG:** propofol + remifentanil 6 ng/ml
- **DRUG:** propofol + remifentanil 0 ng/ml
- **DRUG:** propofol + remifentanil 2 ng/ml
- **DRUG:** propofol + remifentanil 4 ng/ml
- **DRUG:** propofol + remifentanil 6 ng/ml

## Key facts

- **NCT ID:** NCT01053611
- **Lead sponsor:** University Medical Center Groningen
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2009-09
- **Primary completion:** 2010-09
- **Final completion:** 2010-09
- **Target enrollment:** 140 (ACTUAL)
- **Last updated:** 2011-03-25


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01053611

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01053611, "Composite Variability Index Versus Bispectral Index (BIS)". Retrieved via AI Analytics 2026-07-25 from https://api.ai-analytics.org/clinical/NCT01053611. Licensed CC0.

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