MEK Inhibitor MSC1936369B Plus FOLFIRI in Second Line K-Ras Mutated Metastatic Colorectal Cancer (mCRC)
Stopped Conduct the randomized Phase 2 part not recommended due to the achieved MTD for pimasertib (45mg/day) in combination with FOLFIRI
Conditions
- Metastatic Colorectal Cancer
Interventions
- DRUG: Pimasertib
- DRUG: Placebo
- DRUG: FOLFIRI
Sponsor
EMD Serono