# Standard Chemotherapy with or Without Nelarabine or Rituximab in Treating Patients with Newly Diagnosed Acute Lymphoblastic Leukemia

> **NCT01085617** · — · COMPLETED · sponsor: **University College, London**

## Conditions studied

- Leukemia
- Mucositis
- Oral Complications

## Interventions

- **BIOLOGICAL:** palifermin
- **BIOLOGICAL:** rituximab
- **DRUG:** cyclophosphamide
- **DRUG:** cytarabine
- **DRUG:** daunorubicin hydrochloride
- **DRUG:** etoposide
- **DRUG:** fludarabine phosphate
- **DRUG:** imatinib mesylate
- **DRUG:** melphalan
- **DRUG:** mercaptopurine
- **DRUG:** methotrexate
- **DRUG:** nelarabine
- **DRUG:** pegaspargase
- **DRUG:** vincristine sulfate
- **PROCEDURE:** allogeneic hematopoietic stem cell transplantation
- **RADIATION:** total-body irradiation

## Key facts

- **NCT ID:** NCT01085617
- **Lead sponsor:** University College, London
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2010-12
- **Primary completion:** 2025-02-24
- **Final completion:** 2025-02-24
- **Target enrollment:** — (—)
- **Last updated:** 2025-03-30


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01085617

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01085617, "Standard Chemotherapy with or Without Nelarabine or Rituximab in Treating Patients with Newly Diagnosed Acute Lymphoblastic Leukemia". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT01085617. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*