# Allopurinol for Mania: A Randomized Trial Administering Allopurinol vs. Placebo as add-on to Mood Stabilizers and/or Antipsychotics in Patients in a Bipolar Manic Episode

> **NCT01092221** · PHASE3 · COMPLETED · sponsor: **Sheba Medical Center** · enrollment: 180 (actual)

## Conditions studied

- Mania

## Interventions

- **DRUG:** Allopurinol
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT01092221
- **Lead sponsor:** Sheba Medical Center
- **Sponsor class:** OTHER_GOV
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2010-05
- **Primary completion:** 2011-04
- **Final completion:** 2011-04
- **Target enrollment:** 180 (ACTUAL)
- **Last updated:** 2012-05-08


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01092221

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01092221, "Allopurinol for Mania: A Randomized Trial Administering Allopurinol vs. Placebo as add-on to Mood Stabilizers and/or Antipsychotics in Patients in a Bipolar Manic Episode". Retrieved via AI Analytics 2026-06-14 from https://api.ai-analytics.org/clinical/NCT01092221. Licensed CC0.

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