# Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity in Patients With Colon Cancer or Rectal Cancer Receiving Oxaliplatin-Based Combination Chemotherapy

> **NCT01099449** · PHASE3 · COMPLETED · sponsor: **Alliance for Clinical Trials in Oncology** · enrollment: 362 (actual)

## Conditions studied

- Chemotherapeutic Agent Toxicity
- Colorectal Cancer
- Neuropathy
- Neurotoxicity

## Interventions

- **DRUG:** calcium gluconate
- **DRUG:** magnesium sulfate
- **OTHER:** placebo
- **DRUG:** oxaliplatin

## Key facts

- **NCT ID:** NCT01099449
- **Lead sponsor:** Alliance for Clinical Trials in Oncology
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2010-06
- **Primary completion:** 2012-12
- **Final completion:** 2013-03
- **Target enrollment:** 362 (ACTUAL)
- **Last updated:** 2022-11-03

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01099449

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01099449, "Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity in Patients With Colon Cancer or Rectal Cancer Receiving Oxaliplatin-Based Combination Chemotherapy". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT01099449. Licensed CC0.

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